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  • Both in vitro and in vivo data demonstrated that pristimerin induced Noxa expression and apoptosis through activation of the ROS/ER stress/JNK axis in CRC.
  • Fyzikální, chemický nebo biologický faktor v pracovním prostředí, který svou kvalitou nebo kvantitou (koncentrací, intenzitou). Škodlivina, která, je-li jí vystaven lidský organismus, může způsobit nemoc nebo odchylku zdravotního stavu.

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